The effect of elevated levels of serum fats hyperlipidemia- on the long-term implant stability and bone quality has been heavily examined in animal-model studies. This human-based case series was the first clinical study which aimed at clinical and radiographic evaluation of dental implant stability and the changes in bone density in patients with high lipid profile.
Materials and Methods: Twelve female patients, each had a single healed bony site which indicated for implantation together with high serum fasting (Low-density lipoprotein) LDL level (≥160 mg/dl) were included in this study. The clinical implant stability values (ISQ) which were measured using the Resonance Frequency Analysis (RFA) method, and CBCT changes were recorded at baseline and six months post-implant insertion.
Results: All patients showed implant success after six months. There was a significant increase of implant stability after 6 months from (65.92 ± 6.39 ISQ) to (74.42±6.20 ISQ) (p<0.001).
Conclusion: In the light of this very first clinical study on the correlation between dental implant stability and hyperlipidemia, authors didn’t find that the stability of delayed dental implants placed in healed bone sites could be affected by high serum LDL levels and thus hyperlipidemia alone is not considered a major risk factor for dental implant stability.