Background: Management of Temporomandibular disorders (TMD) presents a challenge for the dentist, specifically disc displacement without reduction (DDwR). Various treatment modalities including occlusal appliances with intra-articular injections have been proposed for the treatment of such disorder. Prolotherapy is defined as an injection of growth factors or growth factor production stimulants to grow normal cells or tissue as ligaments and tendons. Several studies have described the application of platelet rich plasma (PRP) via intra-articular injection for curing TMD over recent years. However, these studies used traditional PRP supplemented with anticoagulant. Liq uid phase concentrated growth factor (LPGF) is the latest generation of PRP.
Purpose of the study: To compare clinically, radiographically and biochemically the effect of intra- articular injection of hypertonic dextrose and the intra- articular injection of 2 ml of liquid phase concentrated growth factor with a stabilization appliance as a prolotherapy for temporomandibular joint anterior disc displacement without reduction.
Objectives
To evaluate the role of liquid phase of growth factor in treatment tmds
To evaluate the role of dextrose adas prolothearpy
The efecacy of cad cam stabilising appliance